[3][4] In July 2004, the band entered Black Lounge Studios to begin recording its debut album, Symmetric in Design.

[13] Following the release, despite an outpouring of good reviews and press for the album as well as the success of the single for "Morphogenesis", Scar Symmetry did not embark on tours.

The band released a statement on 11 September 2008 announcing that they had fired vocalist Christian Älvestam, due to touring conflicts, creative and personal differences.

[18] From late October 2009, Scar Symmetry took part in the Neckbreakers Ball Tour alongside Behemoth, DevilDriver and Arsis.

[20] Towards the end of 2010, they toured with Epica in the United States and Canada, starting in West Springfield, Virginia, on 16 November, and finishing in Raleigh, North Carolina, on 18 December.

Drummer Henrik Ohlsson states that the title of the album "seeks to expose the hidden hand of the elite that pull the strings of mankind in order to fulfill their agenda of global domination".

[26] On 9 January 2015, Scar Symmetry announced that vocalist Roberth Karlsson had a child on the way, so the band would not do any touring until the fall of 2015, at the earliest.

[30] On 12 March 2019, Scar Symmetry announced that bassist Andreas Holma had resigned from the band, due to a touring dispute.

[33] On 28 March 2024, Scar Symmetry announced that founding member and drummer Henrik Olsson as well as guitarist Benjamin Ellis had both departed from the band.