Originally formed for promotional tour events, the popularity of the "Fuck You" single and The Lady Killer album led to multiple television appearances reaching an audience of millions in Europe and North America.

[1] Scarlet Fever was formed in May, 2010, for the Cee Lo Green promotional tour of "What Part of Forever" (from The Twilight Saga: Eclipse soundtrack).

They opened for Prince[28] at Madison Square Garden,[29] gave charity performances for Woman's Day Red Dress awards[30][31](Lincoln Center) and the Women's Cancer Research Fund[32][33] (Regent Beverly Wilshire), had a joint concert with Big Boi and Goodie Mob[34] at Club Nokia, then appeared the next week during the NBA All-Star Weekend Slam Dunk Contest[35] at Staples Center.

They returned to Europe for Shockwaves NME Awards Big Gig[36][37] opening for Foo Fighters[38] at Wembley Arena, and the charity Let's Dance for Comic Relief.

[48][50] The April–May American concert tour began at the Coachella Festival, where Cee Lo arrived a half hour late after a delayed flight and heavy traffic into the site.

[54][55] Performances received more favorable reviews at St. Louis, Missouri,[56][57] Morgantown, West Virginia,[58] SunFest in West Palm Beach, Florida,[59] the Schaeffer Eye Center Crawfish Boil in Birmingham, Alabama,[60] the Beale Street Music Festival in Memphis, Tennessee,[61] and the Extravaganza Music Festival in Santa Barbara, California.

[63] Sharon Aguilar reminisced, “Plugged [my guitar] right into the amp; no time for a pedalboard… no fancy in-ear monitors or anything like that… More energy… it ended up being probably my favorite live show that we’ve ever done.”[64] The band also taped television performances for VH1 Storytellers[65] and FUSE TV Talking to Strangers.