Inspired by former Virginia Chief Medical Examiner Marcella Farinelli Fierro MD (retired), she employs advanced forensic technology to unravel mysteries and solve crimes.
Throughout the series, Scarpetta, of Italian descent, navigates her investigative journey across various settings, including Florida, Virginia, and Charleston, South Carolina.
[23][24] In February 2023, Nicole Kidman was cast in the series in the titular role, alongside Jamie Lee Curtis playing Kay's sister Dorothy.
[27] The production crew was seen setting up to film at Little Hats Italian Market in Germantown, Nashville, Tennessee in November 2024, with notices posted around the neighborhood.
[citation needed] Fliers were passed out to neighbors in Old Hickory Village, northeast of downtown Nashville, announcing filming was taking place in early December 2024.