Scey-Maisières (French pronunciation: [sɛ mɛzjɛʁ]) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.

The commune lies 4 km (2.5 mi) west of Ornans on the banks of the Loue.

The commune was formed from the former communes of Scey-en-Varais and Maisières-Notre-Dame.

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