It grows in Louisiana, eastern Arkansas, southwestern Tennessee, Mississippi, Alabama, northwestern Florida, and Georgia, with isolated populations in Kentucky, South Carolina, North Carolina, and Hidalgo.

Few populations are secure due to competition from invasive species (such as Japanese honeysuckle) and habitat loss.

[1] Schisandra glabra is a trailing or twining woody vine[7] sometimes climbing to a height of 20 m (67 feet) or more.

Berries are red, spherical to ellipsoid, up to 15 mm (0.6 inches) long.

It can be found in wooded bluffs, hillsides and ravines at elevations less than 500 m (1650 feet).