Schistostoma is a genus of flies in the family Dolichopodidae, subfamily Microphorinae.

At least 50 extant species have been described in the genus, with 16 from the Palaearctic realm, two from the Oriental realm, four from the Afrotropical realm, and 28 from the Nearctic realm.

Two fossil species have also been described from Burmese amber.

There are also several undescribed species from the Palaearctic realm, and one undescribed species from the Afrotropical realm.

This article related to members of the fly family Dolichopodidae is a stub.