[1] The science centre, which is Northern Ontario's most popular tourist attraction, consists of two snowflake-shaped buildings on the southwestern shore of Ramsey Lake, just south of the downtown core,[1] and a former ice hockey arena which includes the complex's entrance and an IMAX theatre.

Where the walkway reaches the larger snowflake, the Vale Cavern auditorium is frequently used for temporary exhibits, press conferences, film screenings, and other gala events by Science North and the wider community.

From January 22, 2001, to May 10, 2003, the Big Nickel was temporarily located on the primary Science North grounds while Dynamic Earth was under construction.

[17] During the COVID-19 pandemic, Science North engaged in several programs to promote COVID-19 vaccines to youth, families and young adults.

[20] Science North also received a $500,000 grant from the Public Health Agency of Canada's Immunization Partnership Fund to target vaccine hesitant individuals through virtual and in-person activities including podcasts, webinars, digital content and events, museum exhibits and workshops.