Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera.

[4] In hyperemia, there is a visible increase in the blood flow to the sclera (hyperaemia), which accounts for the redness of the eye.

The granuloma is surrounded by multinucleated epitheloid giant cells and new vessels, some of which may show evidence of vasculitis.

Scleritis is best detected by examining the sclera in daylight; retracting the lids helps determine the extent of involvement.

[4] Ancillary tests CT scans, MRIs, and ultrasonographies can be helpful, but do not replace the physical examination.

In mild to moderate cases of scleritis, non-steroidal anti-inflammatory drugs such as flurbiprofen, indomethacin or ibuprofen may be prescribed for pain relief.

[7] If disease control is inadequate with steroids alone, immunosuppressives (Eg: cyclophosphamide, azathioprine, methotrexate) and/or immunomodulators may be considered for treatment.