The district encompasses 48 contributing buildings and 8 contributing objects in the central business district of Scottsburg centered on the Scott County Courthouse.

It developed between about 1873 and 1952, and includes notable examples of Italianate, Romanesque Revival, Gothic Revival, and Stick Style / Eastlake movement style architecture.

Located in the district is the separately listed Scottsburg Depot.

Other notable contributing resources include the Town Tavern (1924), A&P Grocery (1923), Corner Drugstore (c. 1880), Harmon Building (1907), City Hall (1899-1900), Napper's Hospital (1936), Scott Theatre (1946), Scott County Public (Carnegie) Library (1919), Scott County Bank (1906), Prosser's Hardware (1912), and a statue of William Hayden English (1908).

This article about a property in Scott County, Indiana on the National Register of Historic Places is a stub.