"Se Acabo (It's Over)" is the second and final single from A Musical Massacre, a 1999 album by East Coast hip hop group The Beatnuts.

The song is produced by The Beatnuts and features Spanish raps by Juju, Psycho Les and two Merengue rappers: Swinger and Magic Juan.

The track's slow-paced Latin beat samples "Se Acabo" by Marco Antonio Muñiz.

An English remix of "Se Acabo" featuring Method Man can be found on The Beatnuts' 2001 album Take It or Squeeze It.

In 2022, public interest in the Remix version of the song grew, largely thanks to online video-sharing websites such as TikTok.