Blake was born in London, England and raised in Vancouver, British Columbia, Canada.

His mother introduced him to jazz when he was a child and he later attended the Berklee College of Music in Boston.

[3][4][5] He currently plays with his own quintet (featuring David Kikoski, Lage Lund, Bill Stewart, and Matt Clohesy) and has been a regular with the Mingus Big Band as well as many other New York musicians.

Seamus is playing sax on Pink Floyd classic songs as well as Waters solo material.

[citation needed] With Opus 5 With Lea DeLaria With David Kikoski With Victor Lewis With Monday Michiru With Mingus Big Band With Eric Reed With Alex Sipiagin With others