[1] Murphy represented England and won a gold medal at the 1986 Commonwealth Games in Edinburgh, Scotland.

[2][3][4] After winning the prestigious ABA bantamweight title in 1985 and 1986, boxing for St. Albans ABC,[5] he turned professional.

He defended his British Featherweight title for 2 fights losing it to Gary De Roux on Tuesday 5 March 1991.

Sean would then fight once more for the British and Commonwealth Lightweight Title however he was knocked out by Billy Schwer on 16 February 1994 ending his Professional Boxing Career.

After retiring from fighting, Murphy became a trainer at Finchley Amateur Boxing Club, based in Barnet, North London.