Sebastião Lopes de Calheiros e Meneses (24 January 1816 – 20 November 1899) was a Portuguese colonial administrator.
He was born on 24 January 1816 in Geraz do Lima, northern Portugal.
His father was Pedro Lopes de Calheiros e Meneses.
[1] He succeeded António Maria Barreiros Arrobas as governor of Cape Verde on 28 March 1858, and was succeeded by Januário Correia de Almeida in June 1860.
[3] He was Minister of Public Works in the government of Sá da Bandeira (1868-1869).