The secretary of science and technology (Filipino: kalihim ng agham at teknolohiya) is the head of the Department of Science and Technology and is a member of the president's Cabinet.

[1] The position was created in 1987 by then president Corazon Aquino, and was first assumed by Antonio Arizabal.

[2] The current secretary is Renato Solidum Jr., who holds office since July 22, 2022.