Sedalia is an unincorporated town, a post office, and a census-designated place (CDP) located in and governed by Douglas County, Colorado, United States.

The Sedalia post office has the ZIP Code 80135.

[4] At the United States Census 2020, the population of the Sedalia CDP was 177.

[6] Sedalia is located in northern Douglas County along U.S. Route 85, which leads 8 miles (13 km) southeast to Castle Rock, the county seat, and north 24 miles (39 km) to downtown Denver.

The Douglas County School District serves Sedalia.