It is situated on the river Leine, approximately 10 kilometres (6.2 mi) west of Hanover.

Today Seelze mainly plays the role of a bedroom town for commuters working in Hanover.

The local museum and museum of local history (Heimatmuseum Seelze) has been situated in Seelze since moving there in 2018 from a timber-framed building dating to 1856 located the incorporated district of Letter.

The permanent exhibition shows a shoemaker's workshop, a hairdresser's shop from about 1920, a schoolroom of a village from about 1900, and a living room ("Gute Stube") of about 1900.

It is located on the "Freight train bypass Hanover" (Wunstorf – Lehrte) and has 51 classification tracks, 6 main running tracks and workshops for freight cars and electric locomotives on a length of about 6 kilometres (3.7 mi).