Cadayona made it to the final fourteen last November 2009 with Steven Silva and Sarah Lahbati who got the Ultimate Survivor title for male and female, respectively.
In the following week, he was again included in the bottom group together with Princess Snell and the first timer by then, Rox Montealegre, where he was declared as the fourth avenger.
In 2012, Cadayona was a part of the Bea Binene-starred TV series, Alice Bungisngis and her Wonder Walis, as Tomas, one of the assistants of Esmeralda (Jean Garcia).
During the last quarter of the year, he was a part of the Filipino adaptation of the hit Korean series, Coffee Prince, as Baldo, the ever loyal and overly submissive suitor of Andy's sister, Mylene.
Sef also made two independent films, one is under the production of Cinema One entitled Slumber Party; his character was Jonel, a guy who wants to be in a frat and the part of his initiation was to sneak in a house.
Aside from his weekly Friday-night stint in Bubble Gang, He was also hired as the gay character Stefani via Vampire Ang Daddy Ko.
When Party Pilipinas was replaced by Sunday All Stars, Cadayona along with his fellow performers were carried over to join the cast.
But since Sunday All Stars sets a different format compared to its predecessor, He belongs to the Tween Hearts team previously led by Jennylyn Mercado.
He appeared in Mundo Mo'y Akin, where he played Nonoy, who is the friend of Jerome (Alden Richards), who also works in the resort owned by the Carbonels.
Nonoy knows about the special relationship between Jerome Alvarez and Darlene Carbonel (Lauren Young) and soon notices Marilyn Mendoza's (Louise de los Reyes) feelings for his friend.