The Seidel test is used to assess the presence of aqueous humor leakage from anterior chamber of the eye.
[1] Initially the test was used to detect aqueous humor leakage in postoperative patients, later it expanded to detect other causes or anterior chamber leakage.
[1] A fluorescein strip containing 10% fluorescein is applied topically to the affected area, without applying pressure on the eye due to the risk of tissue extrusion.
Any changes in color or surface of the fluorescence area indicate the presence of corneal leakage.
The test is contraindicated in obvious globe rupture, Full-thickness eye laceration, and fluorescein hypersensitivity.