Seine River First Nation (Ojibwe: Jiima’aaganing),[8] previously known as the Rivière la Seine Band, is an Ojibwe First Nation reserve located roughly 300 kilometres (190 mi) west of Thunder Bay, Ontario.

The First Nation have an electoral system of government, consisting of a chief and seven councillors forming their council.

The First Nation is a member of the Pwi-Di-Goo-Zing Ne-Yaa-Zhing Advisory Services, a regional Chiefs Council, which in turn is a member of the Grand Council of Treaty 3, a tribal political organization serving many of the First Nations in northwest Ontario and southeast Manitoba.

The original Mine Centre was a settlement associated with the gold rush around Shoal Lake with a population of 500.

However, many residents moved to the new Mine Centre established by the Canadian Northern Railway after the collapse of the gold rush from 1903 to 1904.