This creek was dammed in the early 20th century creating a small body of water known as Lake Lenape.

The railroad brought hundreds of people from Philadelphia in the summer time, and it became a well known vacation spot for blue collar city workers.

In August 1938, Deutschhorst Country Club, a summer retreat created by the German American Bund, a Pro-Nazi organization moved to the area after purchasing a 40-acre ranch outside of the town.

The group used the area as a summer camp where family functions and activities were pursued in addition to political rallies.

As World War II approached, the club sought to distance itself several times from the Nazi cause in local newspapers and was reported as "almost abandoned" from a lack of use by 1940.

In September 1939, shortly after the start of World War II, the leader of German American Bund, Fritz Julius Kuhn, gave a speech to gathered members of the German American Bund and associated groups such as the World War I German Veteran league known as the Kyffhauser Bund, declaring that with the start of the war Adolf Hitler would "lick the world" in the new conflict.

The camp would eventually be closed after the dissolution of the German American Bund on December 8, 1941, after the Japanese attack on Pearl Harbor.

[3][4][5] The town was also home to the Radium Company of America, which was the largest uranium milling facility in the world at the time.

The company later became instrumental in the production of nuclear weapons,[7] leaving behind a legacy of industrial and radioactive contamination that has been well-hidden by local, county, state, and federal government agencies for decades.

The textile industry has long moved out of the area and Sellersville has become mainly a residential town for people working in the many urban centers that are only a short commute away.

The Holiday House Pool and Recreation Center becomes a hotspot for people to escape the heat during the summer as well.

There are various businesses along Main Street, one being the Washington House, which provide some jobs as well, but largely the town remains a residential area.

Pennsylvania Route 152 passes through Sellersville southwest-northeast along Main Street and Park Avenue, heading northeast into Perkasie.

The East Penn Railroad operates freight service through Sellersville along a branch from Telford to Quakertown along the former SEPTA tracks.

[26][31][32] The borough provides sewer service, with sewage treated at the Pennridge Waste Water Treatment plant.

[33] Cable and internet service in Sellersville is provided by Verizon, Frontier Communications, and Xfinity.

The hospital offers various services including an emergency room, Cancer Care, Orthopaedics, Pediatrics, Surgery, and Women's Health.

Ice storms and large snowstorms depositing ≥ 12 inches (30 cm) of snow occur once every few years, particularly during nor’easters from December through February.