Semyono-Makarensky (Russian: Семёно-Макаренский) is a rural locality (a khutor) in Dzherokayskoye Rural Settlement of Shovgenovsky District, the Republic of Adygea, Russia.

Semyono-Makarensky is located 21 km (13 mi) south of Khakurinokhabl (the district's administrative centre) by road.

Volno-Vesyoly is the nearest rural locality.

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