Born Senbere Teferi Sora,[1] she won her first international medal at the 2011 World Youth Championships in Athletics, placing second in the 1500 m to Kenya's Faith Kipyegon.

[5] Senbere opened the 2013 season with a win at the national junior championships, taking the 3000 metres by a margin of nearly seven seconds.

[6] At the senior Ethiopian championships she made her debut over the 5000 metres and held off competition from Alemitu Heroye to lift her second national title.

[11] She was chosen for the senior Ethiopian team for the 2015 IAAF World Cross Country Championships and, in spite of her suffering an injury in the week before the event,[12] she took to the front pack alongside Agnes Jebet Tirop and the two became the race protagonists, with Tirop eventually beating Senbere in the final 200 m, leaving the Ethiopian with the silver medal.

Senbere's senior debut also saw her head the Ethiopian women to the team title, helped by her compatriot (and bronze medallist) Netsanet Gudeta.