For most of its run, the lead feature was Wonder Woman, a character which had been introduced in All Star Comics #8 (October 1941).

[1] Other characters that appeared included the Black Pirate, the Gay Ghost, Mister Terrific, Wildcat, Sargon the Sorcerer, Hal Mason, the Whip, the Atom, Little Boy Blue, Hop Harrigan, Romance, Inc., Lady Danger, Doctor Pat, and Astra.

The series briefly became a romance title starting with issue #94 (November 1949).

[2] Johnny Peril became the lead feature with issue #107, when the theme of the comic changed to a supernatural/mystery format.

[8] In 2000 and 2001, DC reprinted several of its most notable issues in the Millennium Edition series.