[2] The organisation works with scientists and journalists to put scientific evidence in public discussions about science, and to correct unscientific misinformation.

Since its founding, Sense about Science has contributed to UK public debates about such subjects as alternative medicine, "detoxification" products and detox diets, genetically modified food, avian influenza, chemicals and health, "electrosmog", vaccination, weather and climate, nuclear power, and the use and utility of peer review.

Director Tracey Brown describes such critical thinking as crucial to preventing public health scares based on unpublished information.

[19] The AllTrials campaign calls for all past and present clinical trials to be registered and their full methods and summary results reported.

[24] The campaign has received funding from The Wellcome Trust[25] and is endorsed by figures such as Dara Ó Briain[26] and Derren Brown.

[51] They have received positive coverage in publications from the Royal Society[52] and the U.S. National Science Foundation,[53] and in the writings of scientists such as Ben Goldacre[54] and Steven Novella.

[59] Homeopath Peter Fisher criticised Sense About Science, who have been working closely with NHS primary care trusts on the issue of funding for homeopathy, for being funded by the pharmaceutical industry; Sense About Science responded in a statement to Channel 4 News that "Peter Fisher's desperate comments show about as much grasp of reality as the homeopathic medicine he sells.