Seo made her acting debut in the 2016 television drama Don't Dare to Dream (2016).

[2][3] Her other works include The Smile Has Left Your Eyes (2018), Unlock My Boss (2022), Missing: The Other Side (2020–2023), and The Witch: Part 2.

Seo had always wanted to be an actress, but it took her a long time to persuade her parents to allow her enroll in acting classes.

She enrolled in the Korea National University of Arts in 2013, and it was about that time, while she was looking for part-time work, that she received her first offer to appear in a commercial in 2015.

In the 2016 SBS television program, Don't Dare to Dream, Seo made her acting debut.

She received her big break in the same year by portraying the sister of Shin Hye-sun's character in the popular KBS2 family drama My Golden Life.