Although the origins of the goddess are Celtic, Sequana was subsequently integrated into a Gallo-Roman regional cult of worship after the Roman conquest of Gaul.
The main sites dedicated to her are found in northern Burgundy, especially at the source of the Seine, where archeological excavations have unearthed a temple complex and over a thousand votive offerings.
[1][2][3] The main sanctuary was located at the principal source of the Seine River, near the town of Châtillon-sur-Seine in the Burgundy region.
In the 2nd or 1st century BCE, a healing shrine was built by the Gauls consisting of a "simple square chamber, presumably housing a figure of the goddess, surrounded by an open porch where worshippers could assemble.
"[4] Evidence found during the excavations shows that devotees went on pilgrimages to this sanctuary in order to solicit Sequana's help to restore health or to thank her for past assistance.
[6] Pilgrims were also frequently depicted in the small sculptures as carrying offerings to the goddess, including money, fruit, or a favourite pet dog or bird.
Under the impetus of Baron Haussmann, the city created the park the following year and erected an artificial cave intended to protect the site.
One inscription notes the presence of a sacerdoce Augusti, a priest of the imperial cult dedicated to the worship of the Roman emperors.