Seraph Frissell (August 20, 1840 – 1915) was an American physician and medical writer who specialized in diseases of women and children.

William Frissell, her great-grandfather, was a commissioned officer in the Revolutionary War,[2] and a pioneer settler in western Massachusetts.

He enlisted (from Hebron, Connecticut) in the Revolutionary War, but saw no active service, arriving too late to take part in the Battle of Saratoga.

As a child she was reportedly quiet and diffident, not mingling freely with her schoolmates, and with a deep reverence for religious things.

Frissell's father died when she was eleven years old, leaving her mother financially responsible for herself and six children, Seraph being the third.

Returning home, the next year and a half were devoted to school life and helping a neighbor in household work, thereby earning necessary clothing.

When she was fifteen, her oldest sister decided to seek employment in a woolen mill, and Seraph accompanied her.

She received her diploma from the Department of Medicine and Surgery of the University of Michigan on March 24, 1875,[3][1][4] having had hospital practice in Detroit, Ypsilanti, and Boston.

She also wrote papers on the following topics: "Tobacco," "Contents of a Teapot," "Why I'm a Temperance Doctor," "Hygiene: Why it should be taught in our Public Schools," "Prevention better than Cure," "Colonial Flags and the Evolution of the Stars and Stripes," also "Pioneer Women in Medicine.

She has been superintendent of the Department of Heredity and Health, Woman's Christian Temperance Union, for Hampden County.