Serbia participated at the 2018 Summer Youth Olympics in Buenos Aires, Argentina from 6 October to 18 October 2018.

Serbia qualified one gymnast based on its performance at the 2018 European Junior Championship.

[1] Serbia qualified one athlete based on its performance at one of the Karate Qualification Tournaments.

[2] Serbia qualified two sport shooters based on its performance at the 2017 European Championships.

[3] Serbia qualified one table tennis player based on its performance at the Road to Buenos Aires (Africa) series.