[2] Sereepisuth gained his reputation from targeting mafia leaders like "Kamnan Poh" (Somchai Khunpluem) and "Por Pratunam" (Phaijit Thammarojphinij).

He was born and raised in historic Thonburi (in an area currently assigned to Nonthaburi) to a Teochew background family, his surname was given by King Vajiravudh on 18 March 1914, list 2081.

As assistant director of the 2nd Region Police, Seri was in charge of the 1994 arrest of "Kamnan Poh" in the Khao Mai Kaew land corruption case.

[citation needed][5][6] Sereepisuth came into conflict with Army officer Maj General Khattiya Sawasdipol of the Internal Security Operations Command while investigating the "Por Pratunam" gambling den of Phaijit Thammarojphinij.

There was great speculation about the motivation behind the replacement, as Kowit had earlier arrested several military personnel for alleged involvement in the 2006 Bangkok New Year's Eve bombings.

Police Special Branch Commander Lt-General Theeradech Rodpho-thong refused to file charges of lèse majesté against activists who launched a petition, claiming that the law only applied to members of the royal family.

After numerous bombs were exploded simultaneously on 27 May 2007 in Hat Yai, the police Special Branch claimed it was confident that the explosions were linked to the southern insurgency.

The Special branch cited intelligence reports from two days before the blasts warning that two youngsters from the southern provinces were sneaking explosive devices into Songkhla.

However, the CNS spokesperson claimed that there was reason to believe that the bombs were set off by people who were losing political power, a common euphemism for the deposed government of Thaksin Shinawatra.

He later appealed to the Supreme Court, arguing the loan agreement violated the foundation's objectives and regulations, and that the interest rate was above Bank of Thailand limits.

Sereepisuth's apparent political stance took a vicious turn after the Parliament failed to provide enough approval vote for Pita to become the prime minister.

On the day the Parliament voted whether Pita could be renominated, he skipped the meeting, and shortly after, stated harsh and controversial comments against the younger people, so-called "orange dom", who are mostly voters of the Move Forward Party.

The most devastating actions so far was when Sereepisuth targeted a certain MP from the Move Forward Party, Nakornchai Khunnarong, who had a criminal record and served prison time, more than a decade before the election, in attempt to charge for misqualifications.