The first studies of Serrania de los Churumbelos were carried out by Anglo-Colombian expeditions, "Colombia '98" and "EBA Project", initiatives of Colombian and UK students.

The steep sided slopes, combined with an extensive altitudinal gradient of the Serranía de los Churumbelos have created a number of different ecosystems and micro-habitat zones in the area.

The existence of numerous range extensions in fauna and ecosystems typical of higher altitudes make the Serranía de los Churumbelos an area of high scientific interest.

A previously unexplored table top massif in the Serranía de los Churumbelos, reminiscent of the Tepuis, was explored in 1998 and named Alto Cagadero (1°14'32.32"N, 76°30'28.34"W).

In recent years, the mountain range has come under increased pressure with the completion of the Mocoa-Bogotá highway, the proposed Puerto Asís-Florencia road, and the discovery and exploitation of petroleum and precious metals, all of which threaten a growth in human encroachment.