Sertanense Futebol Clube (Portuguese pronunciation: [sɨɾtɐˈnẽsɨ]), formerly Sertanense Foot-ball Club, is a Portuguese football club based in Sertã.

The largest sports club of Sertã after Vitória de Sernache, in the Castelo Branco district, Sertanense was founded by Casimiro Farinha on February 17, 1934, eventually resorting exclusively to football, after devoting most of its energy to sport fishing, collecting some national trophies.

Twice district champion, in 1998 and 2000, it first reached the third level of national football in 2009.

That summer, former Portugal U-20 goalkeeper José Bizarro – winner of the 1989 FIFA World Youth Championship – took charge of the team.

In that and the previous season's domestic cup, the club faced first division club FC Porto, being ousted 0–4 on both occasions (one at home).Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.