Seskinore or Seskanore (from Irish Seisceann Mhór, meaning 'big marsh/bog')[1][2] is a small village and townland in County Tyrone, Northern Ireland.

The name Seskinore is derived from the Irish Seisceann Mhór, which means "big marsh/bog", and the area to the north on the way to Omagh is characterised by lowland raised bog.

Pike's Province of Ulster (1909) described the area thus: "The country is undulating with bogs in parts which make hunting difficult".

[4] Seskinore Forest, 1 mile (1.6 km) north of the village, is a mixed broadleaf and coniferous woodland which dates from at least 1833.

[5] Little is known about the origins of the village but there is proof that it existed in the early part of the 17th century when at least two of its inhabitants were listed as paying Hearth Tax.