It is located in central Sestao, in close proximity to the city hall and the Santa María church.

Sestao station follows the typical cavern-shaped layout of most underground Metro Bilbao stations designed by Norman Foster, with the main hall located directly above the rail tracks.

The station is also served by Bizkaibus regional bus services.

In 2022, it was announced that a tunnel will connect both banks of the Ibaizabal-Nervión estuary in 2028, incorporating a shuttle train that will connect the Sestao and Areeta (Line 1) stations in four minutes.

[5] Work on the tunnel is scheduled to begin in the summer of 2024, with a planned investment of 450 million euros.