Avett sings and plays guitar, drums, bass, and piano for the band based out of Concord, North Carolina.

Eventually, Nemo disbanded, and with the addition of acoustic instruments and bassist Bob Crawford of Charlotte, The Avett Brothers were formed.

[6] In late 2007, The Avett Brothers added cellist Joe Kwon, a graduate of the University of North Carolina and then-member of Big Pretty and the Red Rockets to their roster.

They made a 2007 appearance on Late Night with Conan O'Brien, signed in 2008 to the Columbia record label, and had the number one album (Emotionalism) on Billboard's Heatseekers chart.

[7] The year brings their first release with Columbia on September 29 and performances as the opening act for both the Dave Matthews Band and Widespread Panic.

The last copies of The Mourning, The Silver, The Bell available were sold in December 2008 during a three-night residency at The Orange Peel in Asheville, North Carolina.

On March 17, 2015, Seth teamed up with Jessica Lea Mayfield to record a set of Elliott Smith's songs.

The two released an album titled Seth Avett & Jessica Lea Mayfield Sing Elliott Smith.