James Seth Littrell (born July 24, 1978) is an American football coach and former player who was most recently the offensive coordinator and quarterbacks coach at the University of Oklahoma before parting ways with the university on October 20, 2024.

[5][6] Littrell started his coaching career as a graduate assistant at Kansas from 2002 to 2004 under Mark Mangino, his former offensive coordinator at Oklahoma.

In Littrell's last season at North Carolina, the team finished 11–3 and first place in the ACC Coastal Division.

With great play from future NFL back Jeffrey Wilson, senior Kishawn McClain, and the future program passing leader sophomore Mason Fine, the team finished the season with a 9–5 record.

Defensive coordinator Phil Bennett took over as interim head coach for the bowl game.

[10] On March 20, 2023, it was announced that Littrell would join the coaching staff at Oklahoma, his alma mater, as an offensive analyst.