The Settembrini class was a pair of submarines built for the Regia Marina (Royal Italian Navy) during the late 1920s.

The Settembrini class was an improved and enlarged version of the preceding Mameli-class submarines.

[1] For surface running, the boats were powered by two 1,500-brake-horsepower (1,119 kW) diesel engines, each driving one propeller shaft.

They were also armed with a single 102-millimeter (4 in) deck gun forward of the conning tower for combat on the surface.

[1][2] During the Spanish Civil War, Luigi Settembrini made one patrol in the Eastern Mediterranean in September 1937 during which she sank a Soviet cargo ship.