He served as Mayor of Newton, Massachusetts, a suburb of Boston, and is a former Democratic candidate for United States Senate in 2012.

[6] His father, Joseph D. Warren, was an advisor for Massachusetts Governor Michael Dukakis's 1988 presidential campaign, and worked in the African-American studies department at Northeastern University before his death in 2010.

[12] Around this time, he served partial terms on the Newton Community Preservation Committee and Economic Development Commission.

[9] In October 2007, Warren left Kerry's office to serve as Naval intelligence specialist in Iraq.

[15][16] In November 2008, Warren formally announced his candidacy, pledging to "protect the sacred trust between the citizens in this city and public servants.

In June 2013, Warren announced that he would block funding for a controversial proposal to construct affordable housing on Beacon Street in Waban for formerly homeless people.

[19] The proposal, called Engine 6, was privately developed and expected to cost $3.1 million; developers had requested about $1.4 million in federal funds managed by the city of Newton to move ahead, but Warren's withdrawal of funding halted future plans for construction.

[20] On May 9, 2011, Setti Warren announced his candidacy to represent Massachusetts in the United States Senate in the 2012 election.

In front of his home and surrounded by family, friends and supporters, Warren called income inequality the "defining issue of our generation."

He has called for single-payer healthcare, free tuition, a new millionaire's tax, and a high-speed rail project across Massachusetts.

[citation needed] Warren later married Elizabeth Tasker "Tassy" Plummer on August 12, 2006, with John Kerry serving as his groomsman.