In 1962, he formed a band that became the Paramounts, later including Westcliff High School pupil Gary Brooker.

During this time, Trower created a local three-piece band called the Jam (not to be confused with the later group with Paul Weller).

[1] Trower then, in June 1967, joined Brooker's new band Procol Harum following the success of their debut May 1967 single "A Whiter Shade of Pale", and remained with them until mid 1971, appearing on the group's first five albums.

[2] Before launching his eponymous band, he joined singer Frankie Miller, ex-Stone the Crows bassist/singer James Dewar, and former Jethro Tull drummer Clive Bunker to form the short-lived combo Jude.

[4] Trower is an influential guitarist who has inspired other guitar legends such as Robert Fripp, who praised him for his string bending and the quality of his sounds, and took lessons from him.

[7] Trower was also a part of the Night of the Guitars II European tour in 1991, organized by Sting and The Police manager Miles Copeland.

The tour featured Ronnie Montrose, Rick Derringer, Saga's Ian Crichton, Dave Sharman, Jan Akkerman and Laurie Wisefield.

In 2007, Trower released a third recording with Jack Bruce, Seven Moons, featuring Gary Husband on drums.

Joining Davey Pattison and Pete Thompson was Glenn Letsch (formerly of Gamma) playing bass.

Ten minutes later (approximately 9:00PM EDT) after playing back-to-back songs "Day of The Eagle" and "Bridge of Sighs", he announced on his microphone that he was not feeling well (he had flu symptoms), handed his guitar to a stage crew, walked backstage and collapsed.

[11] On 18 February 2022, Trower announced his latest studio album, No More Worlds To Conquer, alongside its title track.

[12] Sari Schorr is the featured vocalist on Trower's album, Joyful Sky, which was released on Provogue Records in October 2023.

[13] On June 6, 2024 Trower announced the cancellation of his upcoming tour of the USA scheduled for September/October, due to undisclosed health issues which would necessitate a major operation.

He favors the OCD, Distortion Pro, Fat Boost, CLYDE Deluxe Wah, Deja Vibe 2, Soul-Bender, and a BOSS Chromatic Tuner.