Sewanee (/səˈwɑːni/)[5] is a census-designated place (CDP) in Franklin County, Tennessee, United States.

Sewanee lies on the western edge of the Cumberland Plateau in the southeastern part of Middle Tennessee.

In the western part of Sewanee, the two highways diverge, with US 41A descending the Plateau to the west and continuing toward Cowan and Winchester, and SR 56 descending the Plateau to the south and continuing toward Sherwood and Alabama.

The University of the South campus occupies most of the northern portion of Sewanee, with several small neighborhoods scattered around it.

The climate is characterized by relatively high temperatures and evenly distributed precipitation throughout the year.

[8] As of the 2020 United States census, there were 2,535 people, 469 households, and 249 families residing in the CDP.

34.6% of all households were made up of individuals, and 13.8% had someone living alone who was 65 years of age or older.

The Templeton Library, which was to be the repository of the papers of financier Sir John Templeton, a native of the area, sits prominently on a bluff of the plateau, overlooking the valley below.