The participants live in a facility for 21 days with Dr. Drew Pinsky and Jill Vermeire providing daily one-on-one and group therapy sessions in order to address the psychological and psychiatric roots of their compulsive behavior.

[15] With respect to Sex Rehab in particular, alumnus Duncan Roy has criticized the show's producers for prioritizing titillation and drama over rehabilitation for the patients in terms of casting, filming tactics and their editing choices, claiming that they instigated the behavior that resulted in Kari Ann Peniche's expulsion from the program in order to create a more watchable program.

[8] Duncan Roy moved from his Malibu, California estate to a small Hollywood apartment, where he is co-star Jennifer Ketcham's neighbor.

Ketcham, along with Pinsky, discussed her path into porn and her addictions to both sex and drugs, as well as her recovery, in a March 17, 2010 appearance on The View.

She explained that she had taken a vow of abstinence for a year when she completed treatment, but that after nine months, she met a man with whom she was in a committed monogamous relationship, and who supported her recovery by attending meetings with her.