They are often suspected of being malignant prior to operation, being solid ovarian tumours that tend to occur most commonly in post menopausal women.

[1] Definitive diagnosis of these tumours is based on the histology of tissue obtained in a biopsy or surgical resection.

In a retrospective study of 72 cases in children and adolescents, the histology was important to prognosis.

[14] A prospective study of ovarian sex cord–stromal tumours in children and adolescents began enrolling participants in 2005.

[14] The International Ovarian and Testicular Stromal Tumor Registry is studying these rare tumours and collecting data on them to further research.