Sextus Sentius Caecilianus was a Roman senator, who was active during the first century AD.
The cursus honorum of Caecilianus can be mostly reconstructed from a damaged inscription found in Amiternum (modern San Vittorino), erected by his wife (whose name is lost) and his freedman Atlans.
Next he was commissioned a military tribune with Legio VIII Augusta, at the time stationed in Pannonia.
Upon returning to Rome, Caecilianus was appointed quaestor, and served in the Senatorial province of Baetica; upon completion of this traditional Republican magistracy he would be enrolled in the Senate.
The first was curator alvei Tiberis et riparum, or overseer of civil works concerning the Tiber river.