[1] Daughter of the journalist and Editor-in-Chief of Kayhan, Mehdi Semsar (1929–2003), and of Guity Elahi (founder of Omid Journalism Award), Semsar-de Boisséson is an alumna of Georgetown University School of Foreign Service,[2] where she completed her bachelor's and master's degrees in 1990 at the age of 21 years old.
In 1993, aged 23, she founded Development Institute International (DII), one of France's leading conference providers.
[4] As publisher and owner of European Voice she relaunched its website and created new services.
[8][9][10][11][12] In June 2021, Semsar-de Boisséson stepped down at her request as CEO of POLITICO Europe and joined the advisory board of the publication.
She is serving on the advisory board of Georgetown Institute for Women, Peace and Security.