Shaike Ophir (Hebrew: שייקה אופיר‎; 4 November 1928 – 17 August 1987) was an Israeli film and theater actor, comedian, playwright, screenwriter, director, and the country's first mime.

Ophir acted in 28 films, wrote, directed, and starred in several variety shows and was an accomplished mime, appearing alongside Marcel Marceau.

He reached the peak of his international fame in the title role of Ha-Shoter Azoulay (literally, Officer Azoulay, translated as The Policeman), a film-vehicle by Ephraim Kishon which won a Golden Globe for Best Foreign-Language Film (1972) and was nominated for a Best Foreign Language Academy Award the same year.

In 1985, Ophir starred in a stage adaptation of Janusz Korczak's children's novel King Matt the First, where he played seven different roles.

Shaike Ophir, a heavy smoker, died from lung cancer on 17 August 1987 in Tel Aviv at the age of 58.