[1] Foo Fighters' singer and guitarist Dave Grohl has stated that "Shame Shame" is unlike anything Foo Fighters have ever done before and that the song allowed them to "move into another territory" with their sound on their new album, Medicine at Midnight.

[2] According to the band's bassist Nate Mendel, "Shame Shame" started off as a "just a bunch of clicks from Dave" and originally didn't involve any bass line until he ended up recording extra parts for the song that were ultimately included.

[5][6] The music video was directed by Paola Kudacki and features Sofia Boutella.

Grohl has stated that it was inspired by an unsettling dream he had as a teenager that he had remembered all his life and said that the video was darker than anything they had done before.

[7] With 9.3 million audience impressions for "Shame Shame", Foo Fighters took back the record of most number 1's on the Billboard Rock Airplay chart, which also marked the fastest rise to the top of the chart in four years.