The Shanghai–Kunming Railway or Hukun Railway (simplified Chinese: 沪昆铁路; traditional Chinese: 滬昆鐵路; pinyin: hùkūn tiělù), also known as the Hukun Line, is a major arterial railroad across eastern, south central and southwest China.

The line has a total length of 2,690 km (1,670 mi) and passes through Shanghai Municipality, Zhejiang, Jiangxi, Hunan, Guizhou and Yunnan Province.

Major cities along route include Shanghai, Jiaxing, Hangzhou, Yiwu, Jinhua, Shangrao, Yingtan, Pingxiang, Zhuzhou, Huaihua, Kaili, Guiyang, Anshun, Qujing, and Kunming.

In 2006, after the Ministry of Railways rebuilt sections along route and increased train travel speed, the four lines were collectively referred to as one.

This People's Republic of China rail-related article is a stub.