He was born in a prominent household, descended from the seventh Twelver Shi'a imam, Musa al-Kazim.
He called as Alam al-Huda according to a popular narration said by Shahid Awwal in The book of Arba'in as follow: the Vizier of Abbasid dynasty namely Muhammad ibn al-Husayn became sick.
At her request, the great scholar Shaykh al-Mufīd compiled the book "Ahkām al-Nisā'", which contains the fiqhi rules for women.
Also in Kalam there is proof of the existence of God, he defended the atomist' stance versus that of the Aristotelian notion of substantial change.
Sayyid Murtaḍā acquired the epithet of: "ʿAlam al-Hudā" ("The banner of guidance"), and died at the age of 81 years in 1044 (436 AH).
He was considered a master of kalam, fiqh, usul al-fiqh, literature, grammar, poetry and other fields of knowledge.