Shariff Saydona Mustapha, officially the Municipality of Shariff Saydona Mustapha (Maguindanaon: Inged nu Shariff Saydona Mustapha; Iranun: Inged a Shariff Saydona Mustapha; Tagalog: Bayan ng Shariff Saydona Mustapha), is a municipality in the province of Maguindanao del Sur, Philippines.

Shariff Saydona Mustapha was an Arab missionary from Mecca and a paternal uncle of Shariff Kabungsuwan of Johore (the first Sultan of Maguindanao).

He is the ancestor of the Ampatuan, Mangacop, Masukat and Sangki clans of Maguindanao.

Shariff Saydona Mustapha is politically subdivided into 16 barangays.

Poverty Incidence of Shariff Saydona Mustapha Source: Philippine Statistics Authority[11][12][13][14][15]