[8][9] She was in West Germany[10][11] with her elder sister Sheikh Hasina when her family was assassinated in a military coup by the Bangladesh Army on 15 August 1975.

After relentless campaign in different European countries, in the year 1979 in Sweden, Sheikh Rehana held the first international conference to call for an impartial trial on Bangabandhu Murder.

[15] During her exile in the UK in 1980s, Sheikh Rehana assisted Bangladesh Awami League (BAL) to reach out to European Civil Society and UN Organizations on the plight of Bangladeshi people under undemocratic and brutal military dictatorship it had witnessed from 1975 to 1991.

[22] In 2014 she was allocated a house in Gulshan after Awami League came to power for a token price of 1001 taka following the High Court order which upheld the legality of her prior allotment.

[33][34] Rehana is married to Shafique Ahmed Siddique, retired professor of Department of Accounting & Information Systems, Faculty of Business Studies (FBS), University of Dhaka.

[37] Rehana often accompanied Sheikh Hasina on her official trips including the state funeral of Elizabeth II, Queen of the United Kingdom in 2022 and Coronation of Charles III and Camilla in 2023.