[2] He is best known for his work in experimental elementary particle physics, the Large Hadron Collider beauty experiment (LHCb), and B decays.

[9][10] In 2005, Stone became a LHCb collaborator and served as the Upgrade coordinator from 2008-2011, during which time the project was organized and the letter of intent submitted.

In 2000, he pushed to convert CLEO into a charm factory, which subsequently led to the measurement of the charm-decay constants fD+ and fDs.

He also worked on design and construction of a Ring-imaging Cherenkov detector providing four-σ K-π separation over the full accessible momentum range.

Five-quark resonances, called pentaquarks, were predicted at the dawn of the quark model but were only found after 50 years when Stone and a small team of colleagues uncovered their existence in the LHCb dataset.